1. From the Division of Cardiology, Most Sacred Heart of Jesus Cardiology and Valvular Institute, Sheboygan, WI (N.M.R.); Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN (N.M.R.); Department of Medicine, Division of Cardiology, Hospital Pedro Hispano, Matosinhos, Oporto, Portugal (L.M.); and Department of Cardiology, University Medical School, Oporto, Portugal (L.M.).