Affiliation:
1. From the Department of Medicine (G.H.B., K.T.W.S.), University Hospitals Cleveland Medical Center, OH
2. Case Western Reserve University School of Medicine, Cleveland, OH (G.H.B., K.T.W.S.).
3. Harrington Heart and Vascular Institute (K.T.W.S.), University Hospitals Cleveland Medical Center, OH
Abstract
Peripheral artery disease is an atherosclerotic disease of the lower extremities associated with high cardiovascular mortality. Management of this condition may include lifestyle modifications, medical management, endovascular repair, or surgery. The medical approach to peripheral artery disease is multifaceted and includes cholesterol reduction, antiplatelet therapy, anticoagulation, peripheral vasodilators, blood pressure management, exercise therapy, and smoking cessation. Adherence to this regimen can reduce limb-related complications like critical limb ischemia and amputation, as well as systemic complications of atherosclerosis like stroke and myocardial infarction. Relative to coronary artery disease, peripheral artery disease is an undertreated condition. In this article, we explore the evidence behind medical therapies for the management of peripheral artery disease.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Cardiology and Cardiovascular Medicine
Cited by
87 articles.
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