The Syndrome of Patent Ductus Arteriosus with Pulmonary Hypertension

Author:

HULTGREN HERBERT1,SELZER ARTHUR1,PURDY ANN1,HOLMAN EMILE1,GERBODE FRANK1

Affiliation:

1. From the Departments of Medicine, Pediatrics and Surgery of the Stanford University School of Medicine, San Francisco, Calif.

Abstract

Eight cases of patent ductus arteriosus associated with marked pulmonary hypertension are presented with complete cardiac catheterization studies in six patients and autopsy studies in three cases. Four patients had clear evidence of a "reversed" shunt through the ductus, three presenting the clinical picture of cyanotic congenital heart disease. The authors discuss the nature of the increased resistance of the pulmonary vascular bed which is the basis of the circulatory changes in these cases.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference55 articles.

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4. COURNAND A. BALDWIN J. AND HIMMELSTEIN A.: A Cardiac Catheterization in Congenit al Heart Disease. Monograph. New York The Commonwealth Fund 1949.

5. 5HUBER C.: Piersol's Human Anatomy. M\onograph. Philadelphia J. B. Lippincott 1930.

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