Estimating Total Cerebral Blood Flow From the Initial Slope of Hydrogen Washout Curves-Reference-Cited by-同舟云学术

Estimating Total Cerebral Blood Flow From the Initial Slope of Hydrogen Washout Curves

Published:1975-03 Issue:2 Volume:6 Page:149-152
ISSN:0039-2499
Container-title:Stroke
language:en
Short-container-title:Stroke

Author:

DOYLE T. F.¹,MARTINS A. N.¹,KOBRINE A. I.¹

Affiliation:

1. Neurobiology Division, Armed Forces Radiobiology Research Institute, Defense Nuclear Agency, Bethesda, Maryland 20014; Neurosurgery Service, Walter Reed General Hospital, Washington, D.C. 20012

Abstract

An initial slope index of total cerebral blood flow, measured by the hydrogen clearance technique, shows a high correlation with flows calculated by bicompartmental analysis. In 247 flow measurements done on 41 rhesus monkeys, a linear regression analysis between these two methods of calculating flow shows a correlation coefficient of 0.928 with a standard error about y values of ± 7.63. The initial slope index is not only faster but does not require that a steady state be maintained for ten minutes.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine,Neurology (clinical)

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.STR.6.2.149

Reference5 articles.

1. Sveinsdottir E Thorlof P Risberg J etal: Calculation of regional cerebral blood flow (rCBF): Initial-slope-index compared to height-over-total-area values. In Russell RWR (ed): Brain and Blood Flow. London Pitman Co Ltd p 85-93 1971

2. The Hydrogen Clearance Method in Assessment of Blood Flow in Cortex, White Matter and Deep Nuclei of Baboons

3. Measurement of Local Blood Flow with Hydrogen Gas

4. Fieschi C Bozzao L Agnoli A: Regional clearance of hydrogen as a measure of cerebral blood flow. Acta Neurol Scand 41 (Suppl 14) : 46-52 1965

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