Hypertension and neurofibromatosis. Case report.

Author:

Guthrie G P,Tibbs P A,McAllister R G,Stevens R K,Clark D B

Abstract

A 14-year-old girl with neurofibromatosis presented with severe hypertension. She was subsequently found to have a cerebellar glioblastoma multiforme and vascular lesions producing coarctation of the abdominal aorta and 50% and 95% stenosis of the left and right renal arteries respectively. No evidence of pheochromocytoma was found. After removal of the cerebellar tumor, marked amelioration of the hypertension suggested that the tumor had a major role in the pronounced elevation of her blood pressure. Patients who have both neurofibromatosis and hypertension should be carefully evaluated for these several potential lesions.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Internal Medicine

Reference20 articles.

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2. Feyrter F- Uber die vasculare Neurofibromatose nach Untersuchungen am menschlichen Magendarmschlanch. Virchows Arch (Pathol Anat) 317: 221 1949

3. Arterial hypertension and neurofibromatosis: renal artery stenosis and coarctation of abdominal aorta;Schurch W;Can Med Assoc J,1975

4. Multiple Primary Intracranial Tumors in von Recklinghausen's Neurofibromatosis

5. Association pheochromocytome-neurofibromatose;Veyre B;Nouv Presse Med,1975

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