1. From the Hotchkiss Brain Institute (R.E.M., A.Z., M.S., N.M., S.E.B., D.G.W.), Libin Cardiovascular Institute (R.E.M., A.Z., M.S., N.M., S.E.B., D.G.W.), and Department of Physiology and Pharmacology (R.E.M., A.Z., M.S., N.M., S.E.B., D.G.W.), University of Calgary, Alberta, Canada; and Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada (A.Z., M.S., N.M., S.E.B., D.G.W.).