1. From the Imperial College Healthcare NHS Trust, London, United Kingdom (D.G., M.A.L.); Department of Clinical Pharmacology and Therapeutics (D.G.), Department of Haematology (M.A.L.), and Department of Population Health and Occupational Disease (C.M.), Imperial College London, United Kingdom; Institute for Biomedicine, Eurac Research, Bolzano, Italy (F.D.G.M.); and Centre for Cardiovascular Genetics (A.P.W.), and Division of Biosciences (S.K.S.S.), University College London, United Kingdom.