1. From the Departments of Biochemistry and Biomedical Sciences (M.F., O.D., V.S., D.A., M.M., N.D., B.L.T.), Pathology and Molecular Medicine (J.M., S.A.I.), and Biology (S.A.I.), McMaster University, Hamilton, Ontario, Canada; and Thrombosis and Atherosclerosis Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada (M.F., O.D., V.S., M.M., N.D., B.L.T.).