1. From the Departments of Vascular Medicine (A.v.d.G., M.N.V., S.S., A.C.M.J., J.J.P.K.) and Clinical Epidemiology, Biostatistics and Bioinformatics (T.J.R., B.A.H.), Academic Medical Centre, Amsterdam, the Netherlands; Department of Medicine, Université de Montréal, ECOGENE-21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, Quebec, Canada (D.G., D.B.).