1. From the Cardiovascular Research Center and Cardiology Division (F.A.J.), the Center for Molecular Imaging Research (F.A.J., R.W.), and the Center for Systems Biology (R.W.), Massachusetts General Hospital; the Cardiovascular Division (P.L.), Brigham and Women’s Hospital, Boston, Mass, and the Donald W. Reynolds Cardiovascular Clinical Research Center (F.A.J., P.L., R.W.), Harvard Medical School.