The Transcription Factor Erg Inhibits Vascular Inflammation by Repressing NF-κB Activation and Proinflammatory Gene Expression in Endothelial Cells

Author:

Sperone Andrea1,Dryden Nicola H.1,Birdsey Graeme M.1,Madden Leigh1,Johns Mike1,Evans Paul C.1,Mason Justin C.1,Haskard Dorian O.1,Boyle Joseph J.1,Paleolog Ewa M.1,Randi Anna M.1

Affiliation:

1. From the Vascular Sciences Section (A.S., N.H.D., G.M.B., M.J., P.C.E., J.C.M., D.O.H., J.J.B., and A.M.R.), National Heart and Lung Institute, Imperial College London, London, England; and Kennedy Institute of Rheumatology (L.M. and E.M.P.), Imperial College London, London, England.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

Reference41 articles.

1. Inflammation in atherosclerosis

2. Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells;Pober JS;J Immunol,1986

3. Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region: induction by cytokines and phorbol ester;Voraberger G;J Immunol,1991

4. H2O2 and Tumor Necrosis Factor-α Activate Intercellular Adhesion Molecule 1 (ICAM-1) Gene Transcription through Distinct cis-Regulatory Elements within the ICAM-1 Promoter

5. Transcriptional Regulation of the Intercellular Adhesion Molecule-1 Gene by Inflammatory Cytokines in Human Endothelial Cells

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