1. From the Division of Endocrinology and Metabolism, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan (S.N., H.Y., F.T., M.T., T.O., T.B., K. Okada, J.O., S.I.); and Department of Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan (K. Ohashi, M.S.).