1. From the Department of Genetics, University of North Carolina, Chapel Hill, NC (B.J.B.); Department of Medicine (A.J.L., M.D., H.Q., X.W.), Department of Human Genetics (L.O., E.E., A.J.L.), Department of Microbiology, Immunology, and Molecular Genetics (A.E., A.J.L.), and the Department of Computer Science (E.K., E.E.), University of California Los Angeles, Los Angeles, CA; and Bristol Myers-Squibb, Bioinformatics, Pennington, NJ (I.N., B.G.).