1. From the Department of Internal Medicine (H.M., T.T., J.K., T.I., K.K., T.E.), Circulatory and Body Fluid Regulation, and Department of Pathology (Y.A.), Faculty of Medicine, University of Miyazaki, Miyazaki, Japan; the Department of Nutrition Management (T.T.), Faculty of Health and Nutrition, Minami-Kyushu University, Miyazaki, Japan; and PharmD at Cardiovascular Research (J-P.S.), Bayer HealthCare, Wuppertal, Germany.