1. From the Department of Pharmacology and Toxicology (Y.C., H.C., A.H., D.R.C., M.M.), Wright State University Boonshoft School of Medicine, Dayton, Ohio; Hypertension and Vascular Disease Center (D.I.D., M.C.C.), Wake Forest University School of Medicine, Winston Salem, NC; and Department of Pharmacology and Toxicology (A.C.), Michigan State University School of Medicine, East Lansing, Mich.