1. From the Division of Cardiovascular Medicine (Y.O., M.T., S.U., U.I., K.S.), Department of Medicine; the Divisions of Organ Replacement Research (M.T., E.K.), Functional Genomes (S.U., H.M.), and Genetic Therapeutics (T.O., K.O.), Center for Molecular Medicine; and the Department of Anatomy (K.T., S.O.), Jichi Medical School, Tochigi, Japan, and the Center for Cardiovascular Research (B.C.B.), University of Rochester, Rochester, NY.