Diminished inotropic responses but unaltered toxicity to acetylstrophanthidin in the senescent beagle.

Author:

Guarnieri T,Spurgeon H,Forehlich J P,Weisfeldt M L,Lakatta E G

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference32 articles.

1. Effect of age on the cardiotoxicity of digitalis;Kelliher GJ;J Pharmacol Exp Ther,1976

2. 2: Wollenberger A Jehl J Karsh ML: Influence of age on the sensitivity of the guinea pig and its myocardium to ouabain. J ACS A % Control

3. .0 = 6.3* 21.6 - 3.6* 174.0 = 9.3*

4. .8 = 4.5 8.9 1.4 135.2 = 5.0

5. Ouabain-induced changes in electrophysiologic properties of neonatal, young and adult canine cardiac Purkinje fibers;Rosen MR;J Pharmacol Exp Ther,1975

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