Dexamethasone as Treatment in Cerebrovascular Disease. 1. A Controlled Study in Intracerebral Hemorrhage

Author:

TELLEZ HENRY1,BAUER RAYMOND B.1

Affiliation:

1. Department of Neurology, Wayne State University School of Medicine, 3825 Brush Street, Detroit, Michigan 48201

Abstract

Dexamethasone and a placebo were compared as treatment for 40 patients with intracerebral hemorrhage. Of 19 patients receiving dexamethasone, 17 (89.5%) died during their hospital admission. Of 21 patients receiving a placebo, 16 (76.2%) died. The mortality rate was 100% in 15 patients in the dexamethasone-treated group who were in coma or deep stupor on admission, and the mortality rate was 92% in 12 patients with similar levels of consciousness who received a placebo.Several parameters of the neurological examination showed an improved quality of survival in the Decadron®-treated group, but this was found only at certain days in the study. No overall statistically significant difference was found between the two therapies.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialised Nursing,Cardiology and Cardiovascular Medicine,Clinical Neurology

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