1. From the Fondazione Gabriele Monasterio (A. Gimelli, A. Giorgetti, D.G., A.K., A.R., P.M.), CNR-Regione Toscana, Pisa, Italy; Division of Biostatistics (M.B.), University of South Carolina, Columbia, SC; and Division of Biostatistics (M.B.), Karolinska Institutet, Stockholm, Sweden.