Reduced Na + Current in Native Cardiomyocytes of a Brugada Syndrome Patient Associated With β-2-Syntrophin Mutation-Reference-Cited by-同舟云学术

Reduced Na + Current in Native Cardiomyocytes of a Brugada Syndrome Patient Associated With β-2-Syntrophin Mutation

Published:2018-11 Issue:11 Volume:11 Page:
ISSN:2574-8300
Container-title:Circulation: Genomic and Precision Medicine
language:en
Short-container-title:Circ Genom Precis Med.

Author:

Schmidt Constanze¹²³,Wiedmann Felix¹²³,El-Battrawy Ibrahim³⁴,Fritz Markus⁵,Ratte Antonius¹³,Beller Carsten J.⁵,Lang Siegfried³⁴,Rudic Boris³⁴,Schimpf Rainer³⁴,Akin Ibrahim³⁴,Karck Matthias⁵,Borggrefe Martin³⁴,Katus Hugo A.¹²³,Zhou Xiao-Bo²⁴,Thomas Dierk¹²³

Affiliation:

1. Department of Cardiology, University Hospital Heidelberg (C.S., F.W., A.R., H.A.K., D.T.)

2. DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, University Hospital Heidelberg (C.S., F.W., I.E.-B., S.L., B.R., R.S., I.A., M.B., H.A.K., X.-B.Z., D.T.)

3. HCR (Heidelberg Center for Heart Rhythm Disorders), University Hospital Heidelberg (C.S., F.W., A.R. H.A.K., D.T.)

4. First Department of Medicine, University Medical Center Mannheim, Germany (I.E.-B., S.L., B.R., R.S., I.A., M.B., X.-B.Z.).

5. Department of Cardiac Surgery, University Hospital Heidelberg (M.F., C.J.B., M.K.)

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

Reference5 articles.

1. Syntrophin γ2 Regulates SCN5A Gating by a PDZ Domain-mediated Interaction

2. Cardiac Sodium Channel Na v 1.5 Is Regulated by a Multiprotein Complex Composed of Syntrophins and Dystrophin

3. PDZ Domain–Binding Motif Regulates Cardiomyocyte Compartment-Specific Na V 1.5 Channel Expression and Function

4. Late Sodium Current Inhibition in Acquired and Inherited Ventricular (dys)function and Arrhythmias

5. α-1-Syntrophin Mutation and the Long-QT Syndrome

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