1. From the Department of Medicine, the University of California, San Francisco (B.G.A., H.V.B., S.G.G.); Department of Medicine, Henry Ford Hospital, Detroit, Mich (M.G., M.S., A.A.); Harvard Clinical Research Institute, Boston, Mass (S.A.M., C.M.G.); Department of Medicine, University of Vermont, Burlington (B.E.S.); Genentech, Inc, South San Francisco, Calif (A.C.R., S.G.G., H.V.B.); Florida Cardiology Group, Atlantis, Fla (S.B.); and the Mayo Clinic, Rochester, Minn (R.J.G.).