1. From the Department of Medicine, School of Medicine (K.Y., K.S., K. Naoki, K. Nishio, N.S., K.T., H.K., T.A., A.M.), Keio University, Tokyo, Japan; the Department of Internal Medicine (Y.S.), Kitasato Institute Hospital, Tokyo, Japan; and the Biomedical Department (H.T.), Sankei Corp, Tokyo, Japan.