Impact of the COVID-19 Pandemic on Percutaneous Coronary Intervention in England

Author:

Kwok Chun Shing12ORCID,Gale Chris P.345,Curzen Nick6,de Belder Mark A.7,Ludman Peter8,Lüscher Thomas F.910,Kontopantelis Evangelos11,Roebuck Chris12,Denwood Tom12,Burton Tony12,Hains Julian7ORCID,Deanfield John E.713,Mamas Mamas A.12ORCID

Affiliation:

1. Keele Cardiovascular Research Group, Centre for Prognosis Research, Institute for Primary Care and Health Sciences, Keele University, Stoke-on-Trent, United Kingdom (C.S.K., M.A.M.).

2. Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, United Kingdom (C.S.K., M.A.M.).

3. Leeds Institute of Cardiovascular and Metabolic Medicine (C.P.G.), University of Leeds, United Kingdom.

4. Leeds Institute for Data Analytics (C.P.G.), University of Leeds, United Kingdom.

5. Department of Cardiology, Leeds Teaching Hospitals NHS Trust, United Kingdom (C.P.G.).

6. Wessex Cardiothoracic Unit, Southampton University Hospital Southampton & Faculty of Medicine University of Southampton, United Kingdom (N.C.).

7. National Institute for Cardiovascular Outcomes Research, Barts Health NHS Trust, London, United Kingdom (M.A.d.B., J.H., J.E.D.).

8. Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom (P.L.).

9. Royal Brompton and Harefield Hospital Trust, Imperial College London, United Kingdom (T.F.L.).

10. Centre for Molecular Cardiology, University of Zurich, Switzerland (T.F.L.).

11. Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre (MAHSC), The University of Manchester, United Kingdom (E.K.).

12. NHS Digital, Leeds, United Kingdom (C.R., T.D., T.B.).

13. Department of Cardiology, Great Ormond Street Hospital, University College London, United Kingdom (J.E.D.).

Abstract

Background: The objective of the study was to evaluate changes in percutaneous coronary intervention (PCI) practice in England by analyzing procedural numbers, changes in the clinical presentation, and characteristics of patients and their clinical outcomes during the coronavirus disease 2019 (COVID-19) pandemic. Methods: We conducted a retrospective cohort study of all patients who underwent PCI in England between January 2017 and April 2020 in the British Cardiovascular Intervention Society database. Results: Forty-four hospitals reported PCI procedures for 126 491 patients. There were ≈700 procedures performed each week before the lockdown. After the March 23, 2020 lockdown (11th/12th week in 2020), there was a 49% fall in the number of PCI procedures after the 12th week in 2020. The decrease was greatest in PCI procedures performed for stable angina (66%), followed by non–ST-segment–elevation myocardial infarction (45%), and ST-segment–elevation myocardial infarction (33%). Patients after the lockdown were younger (64.5 versus 65.5 years, P <0.001) and less likely to have diabetes (20.4% versus 24.6%, P <0.001), hypertension (52.0% versus 56.8%, P =0.001), previous myocardial infarction (23.5% versus 26.7%, P =0.008), previous PCI (24.3% versus 28.3%, P =0.001), or previous coronary artery bypass graft (4.6% versus 7.2%, P <0.001) compared with before the lockdown. Conclusions: The lockdown in England has resulted in a significant decline in PCI procedures. Fewer patients underwent PCI for stable angina. This enabled greater capacity for urgent and emergency cases, and a reduced length of stay was seen for such patients. Significant changes in the characteristics of patients towards a lower risk phenotype were observed, particularly for non–ST-segment–elevation myocardial infarction, reflecting a more conservative approach to this cohort.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

Reference21 articles.

1. European Centre for Disease Prevention and Control. COVID-19 Situation Update Worldwide as for 14 May 2019. https://www.ecdc.europa.eu/en/geographical-distribution-2019-ncov-cases. Accessed July 17 2020.

2. Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on ST-Segment–Elevation Myocardial Infarction Care in Hong Kong, China

3. Ludman PF. BCIS National Audit Adult Interventional Procedures. http://www.bcis.org.uk/wp-content/uploads/2020/01/BCIS-Audit-2018-19-data-ALL-24-01-2020-for-web.pdf. Accessed July 17 2020.

4. Reduction in ST-Segment Elevation Cardiac Catheterization Laboratory Activations in the United States During COVID-19 Pandemic

5. Impact of the COVID-19 pandemic on interventional cardiology activity in Spain.;Rodriguez-Leor O;REC Interv Cardiol,2020

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