Management of Myocardial Revascularization in Patients With Stable Coronary Artery Disease Undergoing Transcatheter Aortic Valve Implantation-Reference-Cited by-同舟云学术

Management of Myocardial Revascularization in Patients With Stable Coronary Artery Disease Undergoing Transcatheter Aortic Valve Implantation

Published:2022-12 Issue:12 Volume:15 Page:
ISSN:1941-7640
Container-title:Circulation: Cardiovascular Interventions
language:en
Short-container-title:Circ: Cardiovascular Interventions

Author:

Costa Giuliano¹^ORCID,Pilgrim Thomas²^ORCID,Amat Santos Ignacio J.³,De Backer Ole⁴^ORCID,Kim Won-Keun⁵^ORCID,Barbosa Ribeiro Henrique⁶^ORCID,Saia Francesco⁷^ORCID,Bunc Matjaz¹,Tchetche Didier⁸,Garot Philippe⁹^ORCID,Ribichini Flavio Luciano¹⁰^ORCID,Mylotte Dzxcfewarren¹¹,Burzotta Francesco¹²,Watanabe Yusuke¹³,De Marco Federico¹⁴^ORCID,Tesorio Tullio¹⁵^ORCID,Rheude Tobias¹⁶,Tocci Marco¹⁷^ORCID,Franzone Anna¹⁸,Valvo Roberto¹⁹,Savontaus Mikko²⁰,Wienemann Hendrik²¹^ORCID,Porto Italo²²,Gandolfo Caterina²³,Iadanza Alessandro²⁴^ORCID,Bortone Alessandro Santo²⁵,Mach Markus²⁶^ORCID,Latib Azeem²⁷^ORCID,Biasco Luigi²⁸,Taramasso Maurizio²⁹,Zimarino Marco³⁰^ORCID,Tomii Daijiro²,Nuyens Philippe⁴^ORCID,Sondergaard Lars⁴,Camara Sergio F.⁶^ORCID,Palmerini Tullio⁷,Orzalkiewicz Mateusz⁷^ORCID,Steblovnik Klemen³¹,Degrelle Bastien⁸^ORCID,Gautier Alexandre⁹^ORCID,Del Sole Paolo Alberto¹⁰^ORCID,Mainardi Andrea¹⁰^ORCID,Pighi Michele¹⁰,Lunardi Mattia¹⁰¹¹^ORCID,Kawashima Hideyuki¹³,Criscione Enrico¹⁴^ORCID,Cesario Vincenzo¹⁴,Biancari Fausto¹⁵^ORCID,Zanin Federico¹⁵,Joner Michael¹⁶^ORCID,Esposito Giovanni¹⁸^ORCID,Adam Matti²¹,Grube Eberhard²¹,Baldus Stephan²¹^ORCID,De Marzo Vincenzo²²^ORCID,Piredda Elisa²²,Cannata Stefano²³,Iacovelli Fortunato²⁵^ORCID,Andreas Martin²⁶^ORCID,Frittitta Valentina³⁰^ORCID,Dipietro Elena¹⁹^ORCID,Reddavid Claudia¹⁹^ORCID,Strazzieri Orazio¹⁹^ORCID,Motta Silvia¹⁹^ORCID,Angellotti Domenico¹⁸^ORCID,Sgroi Carmelo¹,Kargoli Faraj²⁷^ORCID,Tamburino Corrado¹,Barbanti Marco³¹^ORCID,

Affiliation:

1. Division of Cardiology, A.O.U. Policlinico “G. Rodolico-San Marco,” Catania, Italy (G.C., C.S., C.T., M.B.).

2. Bern University Hospital, Inselspital, Switzerland (T.P., D.T.).

3. Division of Cardiology, Hospital Clínico Universitario de Valladolid, Spain (I.J.A.C.).

4. The Heart Center, Rigshospitalet, Copehagen University Hospital, Denmark (O.D.B., P.N., L.S.).

5. Kerckhoff Heart Center, Bad Nauheim, Germany (W.-K.K.).

6. Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Brazil (H.B.R., S.F.C.).

7. Dipartimento Cardiovascolare, Policlinico S. Orsola, University of Bologna, Italy (F.S., T.P., M.O.).

8. Clinique Pasteur, Toulouse, France (D.T., B.D.).

9. Institute cardiovasculaire Paris Sud, Massy, France (P.G., A.G.).

10. Division of Cardiology, Azienda Ospedaliera Universitaria Integrata di Verona, Italy (F.L.R., P.A.D.S., A.M., M.P., M.L.).

11. Galway University Hospital, Ireland (D.M., M.L.).

12. IRCSS Policlinico Universitario “Agostino Gemelli,” Università Cattolica del Sacro Cuore, Roma, Italy (F.B.).

13. Department of Cardiology, Teikyo University School of Medicine, Tokyo, Japan (Y.W., H.K.).

14. Division of Cardiology, IRCSS Policlinico San Donato, San Donato Milanese (MI), Italy (F.D.M., E.C., V.C.).

15. Clinica Montevergine, GVM Care & Research, Mercogliano (AV), Italy (T.T., F.B., F.Z.).

16. German Heart Centre, Munich, Germany (T.R., M.J.).

17. Division of Cardiology, Policlinico Umberto I, Roma, Italy (M.T.).

18. Division of Cardiology, AOU Federico II, Università di Napoli, Italy (A.F., G.E., D.A.).

19. University of Catania, Italy (R.V., E.D., C.R., O.S., S.M.).

20. Heart Center, Turku University Hospital, Finland (M.S.).

21. Faculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine, University of Cologne, Germany (H.W., M.A., E.G., S.B.).

22. CardioThoracic and Vascular department, San Martino Policlinico Hospital, Genova, Italy (I.P., V.D.M., E.P.).

23. Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (ISMETT), Palermo, Italy (C.G., S.C.).

24. Azienda Ospedaliera Universitaria Senese, UOSA Cardiologia Interventistica, Policlinico Le Scotte, Siena, Italy (A.I.).

25. Division of University Cardiology, Cardiothoracic Department, Policlinico University Hospital, Bari, Italy (A.S.B., F.I.).

26. Wien University Hospital, Austria (M.M., M.A.).

27. Montefiore Medical Center, New York (A.L., F.K.).

28. Azienda sanitaria locale di Ciriè, Chivasso e Ivrea, ASLTO4, Italy (L.B.).

29. Heart and Valve Center, University Hospital of Zurich, University of Zurich, Switzerland (M.T.).

30. Ospedale “Ss. Annunziata,” Chieti, Italy (M.Z., V.F.).

31. University Medical Centre Ljubljana, Slovenia (M.B., K.S.).

Abstract

Background: The best management of stable coronary artery disease (CAD) in patients undergoing transcatheter aortic valve implantation (TAVI) is still unclear due to the marked inconsistency of the available evidence. Methods: The REVASC-TAVI registry (Management of Myocardial Revascularization in Patients Undergoing Transcatheter Aortic Valve Implantation With Coronary Artery Disease) collected data from 30 centers worldwide on patients undergoing TAVI who had significant, stable CAD at preprocedural work-up. For the purposes of this analysis, patients with either complete or incomplete myocardial revascularization were compared in a propensity score matched analysis, to take into account of baseline confounders. The primary and co-primary outcomes were all-cause death and the composite of all-cause death, stroke, myocardial infarction, and rehospitalization for heart failure, respectively, at 2 years. Results: Among 2407 patients enrolled, 675 pairs of patients achieving complete or incomplete myocardial revascularization were matched. The primary (21.6% versus 18.2%, hazard ratio‚ 0.88 [95% CI, 0.66–1.18]; P =0.38) and co-primary composite (29.0% versus 27.1%, hazard ratio‚ 0.97 [95% CI, 0.76–1.24]; P =0.83) outcome did not differ between patients achieving complete or incomplete myocardial revascularization, respectively. These results were consistent across different prespecified subgroups of patients (< or >75 years of age, Society of Thoracic Surgeons score > or <4%, angina at baseline, diabetes, left ventricular ejection fraction > or <40%, New York Heart Association class I/II or III/IV, renal failure, proximal CAD, multivessel CAD, and left main/proximal anterior descending artery CAD; all P values for interaction >0.10). Conclusions: The present analysis of the REVASC-TAVI registry showed that, among TAVI patients with significant stable CAD found during the TAVI work-up, completeness of myocardial revascularization achieved either staged or concomitantly with TAVI was similar to a strategy of incomplete revascularization in reducing the risk of all cause death, as well as the risk of death, stroke, myocardial infarction, and rehospitalization for heart failure at 2 years, regardless of the clinical and anatomical situations.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

Reference25 articles.

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