1. From the Division of Population Genetics and Prevention (D.Gu, S.S., D.Ge, S.C., J.H.), Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; National Human Genome Center at Beijing (D.Gu, S.S., B.Q.), Beijing, China; Georgia Prevention Institute (D.Ge), Department of Pediatrics, Medical College of Georgia, Augusta; and Institute of Biophysics (B.L., R.C.), Chinese Academy of Sciences, Beijing, China.