1. From the Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine (M.N., I.K., M.H., K.K., N.T., R.K., Y.N., K.T., S.Y., S.U., Y.L., Y.A., K.N.), Japan; the First Department of Internal Medicine, Nara Medical University, Japan (Y.S.); the Center for Tsukuba Advanced Research Alliance, Institute of Applied Biochemistry, University of Tsukuba, Ibaraki, Japan (A.F.); and the Howard Hughes Medical Institute and Department of Pharmacology, University of Texas,...