1. From the Department of Geriatric Medicine (N.K., R.M., M.O., J.H., T.O.) and the Division of Gene Therapy Science (R.M., S.I., M.A., M.S.), Osaka University Medical School, Suita 565, Japan; Central Institute, Shino-Test Corporation (S.Y.), Tokyo, Japan; and Ohmiya Medical Center, Jichi Medical School (I.S.), Omiya, Japan.