1. From the Departments of Nephrology and Endocrinology (E.N., A.N., T.F.), Diabetes Mellitus and Metabolism (H.S.), Human Genetics (K.T.), and Biochemistry and Molecular Biology (T.Y.), University of Tokyo, Tokyo, Japan; Department of Cardiovascular Disease, Tokai University (J.T.), Kanagawa, Japan; Department of Medicine, State University of New York at Stony Brook (S.V.B.), Stony Brook, New York; and Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co, Ltd (Y.O., S.N.), Tsukuba, Japan.