1. From the HELIOS Klinikum-Berlin (B.P., E.S., M.W., A.F., R.D., S.M., F.C.L., D.N.M.), Franz Volhard Clinic and Medical Faculty of the Charité, Humboldt University of Berlin, Germany; Max-Delbrück-Center for Molecular Medicine (P.G., F.C.L., D.N.M.), Berlin-Buch, Germany; Novartis Institutes for Biomedical Research (D.L.F., R.L.W.), East Hanover, NJ; and Department of Pharmacology (I.M.G., A.H.J.D.), Erasmus MC, Rotterdam, The Netherlands.