Reduction in regional cerebral blood flow during normal aging in man.-Reference-Cited by-同舟云学术

Reduction in regional cerebral blood flow during normal aging in man.

Published:1980-01 Issue:1 Volume:11 Page:31-35
ISSN:0039-2499
Container-title:Stroke
language:en
Short-container-title:Stroke

Author:

Melamed E,Lavy S,Bentin S,Cooper G,Rinot Y

Abstract

Regional cerebral blood flow (rCBF) was measured by the 133Xenon inhalation method in a selected group of 44 normal non-hospitalized, normotensive subjects aged 19 to 79 years. rCBF was computed as the initial slope index value (ISI). Advancing age was associated with significant reductions in the mean brain and mean hemispheric ISI as well as in individual ISI levels measured from all areas in both hemispheres. Our findings suggest that decline of rCBF is not limited to normal elderly subjects but that it is a progressive phenomenon which begins at an earlier age.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine,Neurology (clinical)

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.STR.11.1.31

Reference23 articles.

1. Cerebral physiology of the aged: Influence of circulatory disorders. In Gaitz CM (ed) Aging and the Brain. New York;Obrist WD;Plenum Publishing Corporation,1972

2. Regulation of cerebral blood flow. In Himwich HE (ed) Brain Metabolism and Cerebral Disorders. New York, Spectrum Publications;Ingvar DH;Inc.,1976

3. Thompson LW: Cerebral blood flow EEG and behavior in aging. In Terry RD Gershon S (eds) Neurobiology of Aging. Vol 3 New York Raven Press 1976 pp 103-119

4. EFFECTS OF AGING ON CEREBRAL CIRCULATION AND METABOLISM

5. Influence of age and vascular disease on cerebral hemodynamics and metabolism

Cited by 271 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A multi-site 99mTc-HMPAO SPECT study of cerebral blood flow in a community sample of patients with major depression;Translational Psychiatry;2024-06-03

2. Adult human neurogenesis: A view from two schools of thought;IBRO Neuroscience Reports;2023-12

3. Secondary hyperperfusion injury following surgical evacuation for acute isolated epidural hematoma with concurrent cerebral herniation;Frontiers in Neurology;2023-04-17

4. Transcranial doppler velocities in a large healthy population of African children;Heliyon;2023-04

5. Prediction of Intraparenchymal Hemorrhage Progression and Neurologic Outcome in Traumatic Brain Injury Patients Using Radiomics Score and Clinical Parameters;Diagnostics;2022-07-10