Abstract
How should clinicians select the specific drug, operation, splint, exercise, or conversations that will best achieve the therapeutic goal for a given patient? This essay will examine three strategies for doing so: induction from our own, individual prior experiences; abdication to the authority of our teachers and those who write review articles; and deduction from the reports of randomized clinical trials. By means of examples from the recent past, the fallibility of the first two approaches will be illustrated. Then, strategies for critically appraising the published reports of randomized trials will be described. Finally, the reasons why the results of even the proper trials may not be accepted by frontline clinicians will be introduced.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine,Neurology (clinical)
Reference24 articles.
1. Sackett DL Haynes RB Tugwcll P: Clinical epidemiology: a basic science for clinical medicine. Boston Little Brown pp 175-176 1985
2. Miao LL: Gastric freezing: an example of the evaluation of medical therapy by randomized clinical trials. In: JP Bunker BA Barnes and F Mosteller (eds) Costs risks & benefits of surgery. New York: Oxford 1977
3. Achieving "Physiological Gastrectomy" by Gastric Freezing
4. A Cooperative Double-Blind Evaluation of Gastric Freezing in the Treatment of Duodenal Ulcer
5. Influence of Adherence to Treatment and Response of Cholesterol on Mortality in the Coronary Drug Project
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