1. From the Institute for Clinical Evaluative Sciences (S.C., J.V.T., H.C.W., P.C.A., X.W., D.S.L.), Institute for Health Policy, Management, and Evaluation (J.V.T., H.C.W., P.C.A., D.S.L.), Division of Cardiology, Sunnybrook Health Sciences Centre (J.V.T., H.C.W.), and Division of Cardiology, University Health Network and Toronto General Hospital (D.S.L.), University of Toronto, Toronto, ON, Canada; National Heart, Lung, and Blood Institute Framingham Heart Study, Framingham, MA (D.L.); and Center for...