1. From the Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto (K.H., N.K., T.M., M.M., T.K., T.K.); Cardiovascular Center, Osaka Red Cross Hospital, Osaka (D.N., T.I., M.T., H.K.); and Developmental Research Laboratories, Shionogi & Co Ltd, Osaka (A.U., G.K.), Japan. Dr Kambara currently is Director at Shizuoka General Hospital, Shizuoka, Japan.