1. From the Tobacco Research and Treatment Center, General Medicine Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (N.A.R.); University of Ottawa Heart Institute, University of Ottawa, Ottawa, Ontario, Canada (A.L.P.); Division of Clinical Pharmacology and Experimental Therapeutics, Department of Medicine and Bioengineering & Therapeutic Sciences, University of California, San Francisco (N.L.B.); Pfizer Inc, New York, NY (C.A., D.G.); and...