1. From the Heart and Stroke/Richard Lewar Centre of Excellence, University of Toronto, and Division of Cardiology, University Health Network, Toronto, Canada (K.F., G.C., Y.L., P.G., M.H., M.C., P.P.L.); Ontario Cancer Institute and Department of Medical Biophysics, University of Toronto (W.-C.Y.), Toronto, Canada; and the Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan (S.A.).