1. From the Cardiovascular Institute, Beth Israel Deaconess Medical Center, Boston, Mass (D.G., J.K.G., F.d.M.); Genetics and Aging Research Unit (A.L., G.T., K.M.M., J.M., K.R., R.E.T.), Department of Pathology (T.A.), Cardiac Unit (G.W.D., M.J.S.), and Cardiac Surgical Division (T.E.M.), Massachusetts General Hospital, Boston; and Departments of Anesthesia and Medicine, Brigham and Women’s Hospital, Boston, Mass (M.R., A.L., P.A.).