Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis

Author:

Bibli Sofia-Iris12,Hu Jiong12,Sigala Fragiska3,Wittig Ilka2,Heidler Juliana42,Zukunft Sven12,Tsilimigras Diamantis I.3,Randriamboavonjy Voahanginirina12,Wittig Janina142,Kojonazarov Baktybek5,Schürmann Christoph62,Siragusa Mauro12,Siuda Daniel12,Luck Bert12,Abdel Malik Randa12,Filis Konstantinos A.3,Zografos George3,Chen Chen7,Wang Dao Wen7,Pfeilschifter Josef8,Brandes Ralf P.6,Szabo Csaba9,Papapetropoulos Andreas1011,Fleming Ingrid12

Affiliation:

1. Institute for Vascular Signalling, Centre for Molecular Medicine (S.-I.B., J. Hu, S.Z., V.R., J.W., M.S., D.S., B.L., R.A.M., I.F.), Goethe University, Frankfurt am Main, Germany.

2. German Center of Cardiovascular Research, Partner site RheinMain, Frankfurt am Main, Germany (S.-I.B., J. Hu, I.W., J. Heidler, S.Z., V.R., J.W., C. Schürmann, M.S., D.S., B.L., R.A.M., R.P.B., I.F.).

3. First Propedeutic Department of Surgery, Vascular Surgery Division, National and Kapodistrian University of Athens Medical School, Greece (F.S., D.I.T., K.A.F., G.Z.).

4. Functional Proteomics, SFB 815 Core Unit (J.W., J. Heidler), Goethe University, Frankfurt am Main, Germany.

5. Department of Internal Medicine, Universities of Giessen and Marburg Lung Center, Justus Liebig University, Germany (B.K.).

6. Institute for Cardiovascular Physiology (C. Schürmann, R.P.B.), Goethe University, Frankfurt am Main, Germany.

7. Division of Cardiology, Department of Internal Medicine and Gene Therapy Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (C.C., D.W.W.).

8. Pharmacentre Frankfurt/Zentrum für Arzneimittelforschung, Entwicklung und –Sicherheit (J.P.), Goethe University, Frankfurt am Main, Germany.

9. Laboratory of Pharmacology, Department of Medicine, University of Fribourg, Switzerland (C. Szabo).

10. Laboratory of Pharmacology, Department of Pharmacy, National and Kapodistrian University of Athens, Greece (A.P.).

11. Clinical, Experimental Surgery and Translational Research Center, Biomedical Research Foundation of the Academy of Athens, Greece (A.P.).

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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