1. From the Spanish Centre for Pharmacoepidemiological Research, Madrid, Spain (L.A.G.R.); Department of Epidemiology, Harvard School of Public Health, Boston, MA (K.J.L., S.H.-D.); and AstraZeneca R&D, Mölndal, and Institute of Medicine, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden (S.J.).