1. From Clinical Operational Research Unit, University College London, United Kingdom (L.R., C.P., M.U.); Cardiac, Critical Care and Respiratory Division, Great Ormond Street Hospital National Health Service Foundation Trust, London, United Kingdom (I.D.S., M.M., V.T., C.B., K.L.B.); and Paediatric Cardiology, Royal Brompton and Harefield National Health Service Foundation Trust , London, United Kingdom (R.C.F.).