Major Adverse Cardiovascular Events and the Timing and Dose of Corticosteroids in Immune Checkpoint Inhibitor–Associated Myocarditis

Author:

Zhang Lili12,Zlotoff Daniel A.2,Awadalla Magid12,Mahmood Syed S.3,Nohria Anju4,Hassan Malek Z.O.1,Thuny Franck56,Zubiri Leyre7,Chen Carol L.8,Sullivan Ryan J.7,Alvi Raza M.1,Rokicki Adam1,Murphy Sean P.2,Jones-O’Connor Maeve2,Heinzerling Lucie M.9,Barac Ana10,Forrestal Brian J.10,Yang Eric H.11,Gupta Dipti8,Kirchberger Michael C.9,Shah Sachin P.12,Rizvi Muhammad A.13,Sahni Gagan14,Mandawat Anant15,Mahmoudi Michael16,Ganatra Sarju12,Ederhy Stephane17,Zatarain-Nicolas Eduardo18,Groarke John D.4,Tocchetti Carlo G.19,Lyon Alexander R.20,Thavendiranathan Paaladinesh21,Cohen Justine V.7,Reynolds Kerry L.7,Fradley Michael G.22,Neilan Tomas G.12

Affiliation:

1. Cardiovascular Imaging Research Center, Division of Cardiology and Department of Radiology (L. Zhang, M.A., M.Z.O.H., R.M.A., A.R., T.G.N.), Massachusetts General Hospital, Boston.

2. Cardio-Oncology Program, Division of Cardiology, Department of Medicine (L. Zhang, D.A.Z., M.A., S.P.M., M.J.-O., T.G.N.), Massachusetts General Hospital, Boston.

3. Cardiology Division, New York-Presbyterian Hospital, Weill Cornell Medical Center (S.S.M.).

4. Cardio-Oncology Program, Division of Cardiology, Department of Medicine, Brigham and Women’s Hospital, Boston, MA (A.N., J.D.G.).

5. Aix-Marseille University, Assistance Publique – Hôpitaux de Marseille, University Mediterranean Center of Cardio-Oncology, Unit of Heart Failure and Valvular Heart Diseases, Department of Cardiology, Nord Hospital, Center for Cardiovascular and Nutrition Research, France (F.T.).

6. Mediterranean Group of Cardio-Oncology, Marseille, France (F.T.).

7. Division of Oncology and Hematology, Department of Medicine (L. Zubiri, R.J.S., J.V.C., K.L.R.), Massachusetts General Hospital, Boston.

8. Cardiology Service, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York (C.LC., D.G.).

9. Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg, Germany (L.M.H., M.C.K.).

10. Cardio-Oncology Program, MedStar Heart and Vascular Institute, Georgetown University, Washington, DC (A.B., B.J.F.).

11. UCLA Cardio-Oncology Program, Division of Cardiology, Department of Medicine, University of California at Los Angeles (E.H.Y.).

12. Cardiology Division, Lahey Hospital and Medical Center, Burlington, MA (S.P.S., S.G.).

13. Division of Oncology and Hematology, Department of Medicine, Lehigh Valley Hospital, Allentown, PA (M.A.R.).

14. Mount Sinai Hospital, New York (G.S.).

15. Cardio-Oncology Program, Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Emory University School of Medicine, Atlanta, GA (A.M.).

16. Faculty of Medicine, University of Southampton, United Kingdom (M.M.).

17. AP-HP, Saint-Antoine Hospital, Department of Cardiology, UNICO-GRECO Cardio-Oncology Program, Paris, France (S.E.).

18. Service of Cardiology, General University Hospital Gregorio Marañón, Madrid, Spain (E.Z.-N.).

19. Department of Translational Medical Sciences, Federico II University, Naples, Italy (C.G.T.).

20. Cardio-Oncology Program, Royal Brompton Hospital, and Imperial College London, United Kingdom (A.R.L.).

21. Ted Rogers Program in Cardiotoxicity Prevention, Peter Munk Cardiac Center, Division of Cardiology, Toronto General Hospital, University of Toronto, Ontario, Canada (P.T.).

22. Cardio-Oncology Program, Division of Cardiovascular Medicine, Department of Medicine, University of Pennsylvania, Philadelphia (M.G.F.).

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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