Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation

Author:

Ramírez Cristina M.12,Zhang Xinbo12,Bandyopadhyay Chirosree3,Rotllan Noemi12,Sugiyama Michael G.4,Aryal Binod12,Liu Xinran5,He Shun6,Kraehling Jan R.1,Ulrich Victoria1,Lin Chin Sheng7,Velazquez Heino8,Lasunción Miguel A.3,Li Guangxin910,Suárez Yajaira12,Tellides George910,Swirski Filip K.6,Lee Warren L.4,Schwartz Martin A.111213,Sessa William C.114,Fernández-Hernando Carlos12

Affiliation:

1. Vascular Biology and Therapeutics Program (C.M.R., X.Z., N.R., B.A., J.R.K., V.U., Y.S., W.C.S., C.F.-H.), Yale University School of Medicine, New Haven, CT.

2. Integrative Cell Signaling and Neurobiology of Metabolism Program, Department of Comparative Medicine and Department of Pathology (C.M.R., X.Z., N.R., B.A., Y.S., C.F.-H.), Yale University School of Medicine, New Haven, CT.

3. Cardiovascular Research Center, Department of Internal Medicine and Cell Biology (C.B., M.A.S.), Yale University School of Medicine, New Haven, CT.

4. Keenan Research Centre and Departments of Laboratory Medicine and Pathobiology, Biochemistry and Medicine, University of Toronto, ON, Canada (M.G.S., W.L.L.).

5. Department of Cell Biology (X.L.), Yale University School of Medicine, New Haven, CT.

6. Center for System Biology, Massachusetts General Hospital and Harvard Medical School, Boston (S.H., F.K.S.).

7. Division of Cardiology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan (C.S.L.).

8. Section of Nephrology (H.V.), Yale University School of Medicine, New Haven, CT.

9. Departments of Cell Biology and Biomedical Engineering (G.L., G.T.), Yale University School of Medicine, New Haven, CT.

10. Department of Surgery (G.L., G.T.), Yale University School of Medicine, New Haven, CT.

11. Department of Cell Biology (M.A.S.), Yale University School of Medicine, New Haven, CT.

12. Departamento de Bioquímica-Investigación, Hospital Ramón y Cajal, IRyCIS, Madrid, Spain (M.A.L.).

13. CIBER de Fisiopatología de la Obesidad y Nutrición, ISCIII, Madrid, Spain (M.A.L.).

14. Department of Pharmacology (W.C.S.), Yale University School of Medicine, New Haven, CT.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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