1. From the Calgary Stroke Program (E.E.S., N.S.), Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada; Duke Clinical Research Institute (D.D., D.M.O., A.F.H., E.D.P.), Durham, NC; Department of Epidemiology (M.J.R.), Michigan State University, East Lansing; Department of Neurology (J.L.S.) and Division of Cardiology (G.C.F.), University of California, Los Angeles; and Stroke Service (L.H.S.), Massachusetts General Hospital, Boston, Mass.