1. From the Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josée and Henry R. Kravis Cardiovascular Health Center, Mount Sinai School of Medicine, New York (J.S.C., R.L.N., V.F.), the Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (V.F.), and the University of Michigan Health System and Medical School, Division of Cardiovascular Medicine, Ann Arbor (P.V.).