1. From Lankenau Institute for Medical Research, Wynnewood, Pa (M.H.U.U., M.D.E.); Mercy Catholic Medical Center, Darby, Pa (M.H.U.U.); Section of Vascular Medicine, University of Pennsylvania Health System, Philadelphia (M.H.U.U.); and ARYx Therapeutics Inc, Fremont, Calif (D.E., P.M., D.C.).