Targeting Cadherin-11 Prevents Notch1-Mediated Calcific Aortic Valve Disease
Author:
Affiliation:
1. From Department of Biomedical Engineering, Vanderbilt University, Nashville, TN.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Link
https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.117.027771
Reference5 articles.
1. Altered DNA Methylation of Long Noncoding RNA H19 in Calcific Aortic Valve Disease Promotes Mineralization by Silencing NOTCH1
2. Mutations in NOTCH1 cause aortic valve disease
3. Cadherin-11 Regulates Cell–Cell Tension Necessary for Calcific Nodule Formation by Valvular Myofibroblasts
4. Notch1 Mutation Leads to Valvular Calcification Through Enhanced Myofibroblast Mechanotransduction
5. Lnc-ing NOTCH1 to Idiopathic Calcific Aortic Valve Disease
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