Cholesterol Metabolism in Gonadectomized Rats-Reference-Cited by-同舟云学术

Cholesterol Metabolism in Gonadectomized Rats

Published:1958-03 Issue:2 Volume:6 Page:172-177
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circulation Research

Author:

COLEMAN RICHARD D.¹,CHEN YU MIN¹,ALFIN-SLATER ROSLYN B.¹

Affiliation:

1. Laboratory of Nutrition, Department of Biochemistry and Nutrition, University of Southern California School of Medicine, Los Angeles, Calif

Abstract

In studies in which tissue concentrations of cholesterol and total lipids were determined in male and female rats fed a control diet containing fat, the effects of gonadectomy were much smaller than in animals fed a fat-free diet in which gonadectomy tended to reverse the sex differences observed in these lipid values. Other phases of lipid metabolism were shown to be sex-linked as well. Gonadectomy resulted in decreased synthesis of cholesterol in rat liver slices and changes in the fatty acid composition of cholesterol esters in the liver.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.RES.6.2.172

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