Determinations of DPN (TPN) Thiamine, Amino Acids and Amino Sugars in Blood of Animals with Experimental Myocardial Infarction

Author:

CABRERA G.1,BEUREN A.1,BING R. J.1

Affiliation:

1. Department of Medicine, Washington University School of Medicine and the Washington University Medical Service, Veterans Administration Hospital, St. Louis, Mo

Abstract

An investigation was made of the possible release from heart muscle of substances of small molecular weight following experimental myocardial infarction. These resulting chemical changes in coronary vein blood may be due to metabolic alterations of the cell which would either precede cell death or take place in cells with reversible metabolic changes. The coronary arteriovenous differences of pyridine nucleotides, thiamine and its phosphorylated derivatives, amino acids and amino sugars were investigated. No changes from the control were found. The negative results may have been caused by the rapid turnover of these substances in blood.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference12 articles.

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3. The fluorometric measurement of pyridine nucleotides;LOWRT O. H.;J. Biol. Chem.,1957

4. BcRcn, n . B., BESSET , O. A. , Low, R. H. , AXD LOWRT, 0. H.: The determination of thianiine and thiamine phosphates in small quantities of blood and blood cells. J. Biol. Chem. 198 : 477 , 1952 .

5. A study of the behaviour of some sixty amino-acids and other ninhydrin-reacting substances on phenol-‘collidine’ filter-paper chromatograms, with notes as to the occurrence of some of them in biological fluids

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1. Studies of Plasma and Urinary Amino Nitrogen in Myocardial Infarction;Acta Medica Scandinavica;2009-04-24

2. Die Coronarerkrankungen. Coronarinsuffizienz, Angina pectoris und Herzinfarkt;Angeborene Herz- und Gefässmissbildungen Durchblutungsstörungen des Herzmuskels;1960

3. Heart;Annual Review of Physiology;1959-03

4. Der Stoffwechsel des Herzens;Ergebnisse der Inneren Medizin und Kinderheilkunde;1959

5. MYOCARDIAL METABOLISM;Annals of Internal Medicine;1958-11-01

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