Computer Simulation of the Propagation Process in Excitation of the Ventricles

Author:

OKAJIMA MITSUHARU1,FUJINO TETSURO1,KOBAYASHI TOSHIJI1,YAMADA KAZUO1

Affiliation:

1. Division of Circulation and Respiration, Research Institute of Environmental Medicine, Nagoya University Furo-cho, Chikusa-ku, Nagoya, Japan

Abstract

Simulation by a digital computer of propagated excitation in the ventricular myocardium has been accomplished. Experience with the program in normal conduction and in one example of abnormal conduction, an extrasystole, is presented. Results of the simulation process were in harmony with observations in animal experiments. This justifies attempts to apply this scheme to the analysis of abnormal ventricular excitation caused by other disturbances. A crucial role of the Purkinje network in determining the course of excitation spread was recognized in the simulated process of both normal beats and extrasystoles. New knowledge is expected from this scheme when applied to other types of abnormal excitation. The possibility of combining the scheme with a method of reconstruction of QRS complexes by means of "transfer impedance" values was pointed out.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference11 articles.

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2. VENTRICULAR DEPOLARIZATION AND THE GENESIS OF QRS

3. Gross Demonstration of the Mammalian Atrioventricular Bundle by A Periodic Acid-Schiff Procedure

4. HOFFMAN B. F. AND CBANEFIELD P. F.: Electrophysiology of the heart. New York Mc-Graw-Hill Book Co. 1960 pp. 79 178-179 207.

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