Affiliation:
1. Department of Medicine, New York University College of Medicine, and the Electrocardiographic Laboratory of the Third (New York University) Medical Division of Bellevue Hospital, New York, N. Y.
Abstract
By means of an intracellular capillary electrode the effects of barium chloride on the resting and action potentials of ventricular fibers of the frog were recorded in hearts with circulation intact and hearts isolated and perfused. The changes were essentially similar in both preparations. The major change observed was a statistically significant (p <0.01) increase in duration of the action potential. Changes were also observed in the magnitude of the resting and action potential, in the rate of depolarization, and in rhythm, but these did not occur invariably. By a series of exclusion experiments it was demonstrated that barium has a direct effect on the ventricular fibers of the frog's heart.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Cardiology and Cardiovascular Medicine,Physiology
Cited by
32 articles.
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