Affiliation:
1. Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55901
Abstract
Cardiac and aortic pressures were recorded after stellate ganglionectomy and vagotomy. Acute heart block was produced by injecting the atrioventricular node, and atrial and ventricular systoles were controlled electronically to occur independently or in any desired relationship. Angiocardiograms recorded on video tape after injections of 4 ml 69% Renovist into the left ventricle were analyzed with a videodensitometer able to detect small refluxes of contrast medium into the left atrium and correlate them with phases of the cardiac cycle. When ventricular driving was temporarily suspended but atrial driving continued, pressure records indicated mitral valve closure after each atrial systole, but reflux of contrast medium into the atrium occurred after each systole not followed by a normally sequenced ventricular systole. Driving with a 2: 1 atrioventricular stimulation resulted in reflux, with the alternate atrial contraction dissociated from ventricular systole. Thus, the mitral valve was not effectively closed by atrial systoles that were not followed by normally sequenced ventricular systoles.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Cardiology and Cardiovascular Medicine,Physiology
Reference23 articles.
1. Movements of the mitral cusps in relation to the cardiac cycle;DEAN A. L.;Am. J. Physiol.,1916
2. TWO modes of closure of the heart valves;HENDERSON Y.;Heart,1912
3. Effect of atrial systole on ventricular pressure and closure of the A-V valves;LITTLE R. C;Am. J. Physiol.,1951
4. Influence of atrial contraction and relaxation on closure of mitral valve: Observations on effects of autonomic nerve activity;SAHNOFF S. J.;Circulation Res.,1962
5. Hemodynamic effects of altering the timing of atrial systole. Am;SKINNER N. S.;J. Physiol.,1963
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